Researchers at Johns Hopkins identified “hot spots” in the Topo protein that are targeted by the immune system in scleroderma patients with different genetic backgrounds, which may help us understand why the immune system attacks healthy tissues in this autoimmune disease.
This study from the Johns Hopkins Scleroderma Center found that scleroderma patients with multiple autoimmune responses may be protected from the development of cancer.
We report results from analysis of clinical, laboratory and socio-demographic data provided by the GRASP cohort, which has enhanced our knowledge about factors associated with significant manifestations of scleroderma in African Americans.
A new study found that people with scleroderma who have muscle weakness due to the accumulation of fibrous tissue in their muscles, are at risk for severe disease outcomes including death from heart disease.
